• Issue

    Diabetes, Obesity and Metabolism: Volume 26, Issue 1

    C1, 1-404
    January 2024
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COVER IMAGE

Free Access

Front Cover

Nikolaos Perakakis MD,  Stefan R. Bornstein MD,  Andreas L. Birkenfeld MD,  Andreas Linkermann MD,  Münevver Demir MD,  Stefan D. Anker MD,  Gerasimos Filippatos MD,  Bertram Pitt MD,  Peter Rossing MD,  Luis M. Ruilope MD,  Peter Kolkhof PhD,  Robert Lawatscheck MD,  Charlie Scott MSc,  George L. Bakris MD,  FIDELIO-DKD and FIGARO-DKD investigators , 
  • Pages: C1
  • First Published: 10 December 2023
Front Cover Issue 1, 2024

The cover image is based on the Original Article Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis by Nikolaos Perakakis MD et al., https://doi.org/10.1111/dom.15305.

ISSUE INFORMATION

Free Access

Diabetes, Obesity and Metabolism

  • Pages: 1-2
  • First Published: 10 December 2023

REVIEW ARTICLES

Role of the tripartite motif-containing (TRIM) family of proteins in insulin resistance and related disorders

Jianrong Chen MD,  Xianjie Feng MB,  Xu Zhou MD,  Yong Li PhD, 
  • Pages: 3-15
  • First Published: 19 September 2023
Open Access

Pancreatic islet cell plasticity: Pathogenic or therapeutically exploitable?

Neil Tanday PhD,  Andrei I. Tarasov PhD,  R. Charlotte Moffett PhD,  Peter R. Flatt PhD,  Nigel Irwin PhD, 
  • Pages: 16-31
  • First Published: 16 October 2023

ORIGINAL ARTICLES

Human placenta-derived mesenchymal stem cells ameliorate diabetic kidney disease by modulating the T helper 17 cell/ regulatory T-cell balance through the programmed death 1 / programmed death-ligand 1 pathway

Jiao Wang MD,  Honghong Liu MS,  Guanru Yue MS,  Yuanyuan Deng MS,  Wei Cai MD,  Jixiong Xu MD, 
  • Pages: 32-45
  • First Published: 18 September 2023

Intermittently scanned continuous glucose monitoring and hypoglycaemia awareness in drivers with diabetes: Insights from the Association of British Clinical Diabetologists Nationwide audit

Charlotte Mark-Wagstaff MBChB,  Harshal Deshmukh MBBS,  Emma G. Wilmot MBChB,  Neil Walker MBBS,  Dennis Barnes MBBS,  Vernon Parfitt MBChB,  Simon Saunders MBChB,  Rob Gregory MBBS,  Pratik Choudhary MBBS,  Jane Patmore MBBS,  Chris Walton MBBS,  Robert E. J. Ryder MBChB,  Thozhukat Sathyapalan MBBS, 
  • Pages: 46-53
  • First Published: 17 September 2023
Open Access

Albuminuria-lowering effect of adding semaglutide on top of empagliflozin in individuals with type 2 diabetes: A randomized and placebo-controlled study

Suvanjaa Sivalingam MD,  Victor Soendergaard Wasehuus MD,  Viktor Rotbain Curovic MD,  Martin Bæk Blond PhD,  Tine W. Hansen PhD,  Frederik Persson DMSc,  Peter Rossing DMSc, 
  • Pages: 54-64
  • First Published: 18 September 2023
Open Access

Abolishing β-arrestin recruitment is necessary for the full metabolic benefits of G protein-biased glucagon-like peptide-1 receptor agonists

Charlotte E. Hinds PhD,  Ellie Peace BSc,  Shiqian Chen MRes,  Iona Davies MRes,  Liliane El Eid MRes,  Alejandra Tomas PhD,  Tricia Tan MD,  James Minnion PhD,  Ben Jones MD,  Stephen R. Bloom MD, 
  • Pages: 65-77
  • First Published: 05 October 2023
Open Access

Comparison of Control-IQ and open-source AndroidAPS automated insulin delivery systems in adults with type 1 diabetes: The CODIAC study

Quoc Dat Do MD,  Aneta Hásková MSc,  Lucie Radovnická MD,  Judita Konečná MSc,  Eva Horová MD,  Christopher G. Parkin MS,  George Grunberger MD,  Martin Prázný MD,  Jan Šoupal MD, 
  • Pages: 78-84
  • First Published: 25 September 2023

Global burden of diabetes mellitus from 1990 to 2019 attributable to dietary factors: An analysis of the Global Burden of Disease Study 2019

Ting Hong MD,  Fangfang Sun MD,  Qiwei Wang MD,  Xufeng Chen MD,  Kun Han PhD, 
  • Pages: 85-96
  • First Published: 25 September 2023

Differential effect of interventions in patients with prediabetes stratified by a machine learning-based diabetes progression prediction model

Xiantong Zou MD,  Yingying Luo MD,  Qi Huang MD,  Zhanxing Zhu PhD,  Yufeng Li MD,  Xiuying Zhang MD,  Xianghai Zhou MD,  Linong Ji MD, 
  • Pages: 97-107
  • First Published: 01 October 2023

Risk of thyroid cancer associated with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes: A population-based cohort study

Sungho Bea PharmD,  Heejun Son MD,  Jae Hyun Bae MD,  Sun Wook Cho MD,  Ju-Young Shin PhD,  Young Min Cho MD, 
  • Pages: 108-117
  • First Published: 21 September 2023
Open Access

Telehealth use and its impact on clinical outcomes in patients with type 2 diabetes during the COVID-19 pandemic

Yixue Shao PhD,  Lizheng Shi PhD,  Elizabeth Nauman PhD,  Eboni Price-Haywood MD,  Charles Stoecker PhD, 
  • Pages: 118-125
  • First Published: 19 September 2023
Open Access

Glycaemic control, body weight, and safety of tirzepatide versus dulaglutide by baseline glycated haemoglobin level in Japanese patients with type 2 diabetes: A subgroup analysis of the SURPASS J-mono study

Takeshi Osonoi MD,  Tomonori Oura MSc,  Tetsuaki Hirase MD, 
  • Pages: 126-134
  • First Published: 04 October 2023

Multi-tissue transcriptome-wide association study reveals susceptibility genes and drug targets for insulin resistance-relevant phenotypes

Yuan-Yuan Duan BS,  Xin Ke PhD,  Hao Wu BS,  Shi Yao PhD,  Wei Shi MSc,  Ji-Zhou Han BS,  Ren-Jie Zhu BS,  Jia-Hao Wang BS,  Ying-Ying Jia BS,  Tie-Lin Yang PhD,  Meng Li MD,  Yan Guo PhD, 
  • Pages: 135-147
  • First Published: 01 October 2023
Open Access

Societal health and economic burden of cardiovascular diseases in the population with type 2 diabetes in Qatar. A 10-year forecasting model

Dina Abushanab MSc,  Daoud Al-Badriyeh PhD,  Clara Marquina PhD,  Danny Liew PhD,  Manal Al-Zaidan PharmD,  Mohammed Ghaith Al-Kuwari MD,  Jazeel Abdulmajeed PhD,  Zanfina Ademi PhD, 
  • Pages: 148-159
  • First Published: 16 October 2023

Open Access

The impact of type 2 diabetes and glycaemic control on mortality and clinical outcomes in hospitalized patients with COVID-19 in the capital region of Denmark

Vivian Kliim-Hansen MD,  Karl S. Johansson MD,  Lærke S. Gasbjerg PhD,  Espen Jimenez-Solem PhD,  Tonny S. Petersen MD,  Martin E. Nyeland PhD,  Matilde Winther-Jensen PhD,  Mikkel Zöllner Ankarfeldt PhD,  Miriam G. Pedersen PhD,  Anne-Marie Ellegaard PhD,  Filip K. Knop MD,  Mikkel B. Christensen MD, 
  • Pages: 160-168
  • First Published: 05 October 2023

Construction and validation of a nomogram for predicting diabetes remission at 3 months after bariatric surgery in patients with obesity combined with type 2 diabetes mellitus

Kaisheng Yuan MD,  Bing Wu MD,  Ruiqi Zeng MM,  Fuqing Zhou MM,  Ruixiang Hu MD,  Cunchuan Wang MD, 
  • Pages: 169-179
  • First Published: 09 October 2023

Repeated detection of non-alcoholic fatty liver disease increases the incidence risk of type 2 diabetes in young adults

Jin Hwa Kim MD,  Young Sang Lyu MD,  Mee Kyoung Kim MD,  Sang Yong Kim MD,  Ki-Hyun Baek MD,  Ki-Ho Song MD,  Kyungdo Han PHD,  Hyuk-Sang Kwon MD, 
  • Pages: 180-190
  • First Published: 23 October 2023
Open Access

Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis

Nikolaos Perakakis MD,  Stefan R. Bornstein MD,  Andreas L. Birkenfeld MD,  Andreas Linkermann MD,  Münevver Demir MD,  Stefan D. Anker MD,  Gerasimos Filippatos MD,  Bertram Pitt MD,  Peter Rossing MD,  Luis M. Ruilope MD,  Peter Kolkhof PhD,  Robert Lawatscheck MD,  Charlie Scott MSc,  George L. Bakris MD,  FIDELIO-DKD and FIGARO-DKD investigators , 
  • Pages: 191-200
  • First Published: 10 October 2023

Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

Signe Foghsgaard MD,  Louise Vedtofte MSc,  Emilie S. Andersen MD,  Emilie Bahne MD,  Camilla Andreasen MD,  Anne L. Sørensen MSc,  Julie L. Forman MSc,  Elisabeth R. Mathiesen MD,  Jens A. Svare MD,  Tine D. Clausen MD,  Peter Damm MD,  Jens J. Holst MD,  Filip K. Knop MD,  Tina Vilsbøll MD, 
  • Pages: 201-214
  • First Published: 17 October 2023
Open Access

Ultra rapid lispro (Lyumjev®) shortens time to recovery from hyperglycaemia compared to Humalog® in individuals with type 1 diabetes on continuous subcutaneous insulin infusion

Jennifer Leohr PhD,  Mary Anne Dellva MS,  Elizabeth LaBell BS,  David E. Coutant PhD,  Jorge Arrubla MD,  Leona Plum-Mörschel MD,  Eric Zijlstra PhD,  Tsuyoshi Fukuda PhD,  Thomas Hardy MD, 
  • Pages: 215-223
  • First Published: 09 October 2023

Types of diabetes during pregnancy and risk of depression and anxiety in offspring from childhood to young adulthood

Anny H. Xiang PhD,  Jane C. Lin MS,  Ting Chow MPH,  Mayra P. Martinez MPH,  Sonya Negriff PhD,  Kathleen A. Page MD,  Rob McConnell MD,  Sarah A. Carter PhD, 
  • Pages: 224-232
  • First Published: 12 October 2023
Open Access

Proportion of participants with type 2 diabetes achieving a metabolic composite endpoint with once-weekly semaglutide treatment versus comparators: Post hoc pooled analysis from SUSTAIN 1-5, 7-10 and SUSTAIN China

Linong Ji MD,  A. J. Ahmann MD,  B. Ahrén MD,  M. S. Capehorn BMedSciMBChB,  P. Hu MD,  I. Lingvay MD,  W. Liu MS,  H. W. Rodbard MD,  Z. Shen MSc,  C. Sorli MD, 
  • Pages: 233-241
  • First Published: 12 October 2023

The effect of metformin on urate metabolism: Findings from observational and Mendelian randomization analyses

Huajie Dai MD,  Tianzhichao Hou MD,  Qi Wang MD,  Zheng Zhu MD,  Yijie Zhu MD,  Zhiyun Zhao PhD,  Mian Li PhD,  Yu Xu PhD,  Jieli Lu PhD,  Tiange Wang PhD,  Guang Ning PhD,  Weiqing Wang PhD,  Yufang Bi PhD,  Jie Zheng PhD,  Min Xu PhD, 
  • Pages: 242-250
  • First Published: 09 October 2023
Open Access

Bone marrow metabolism is affected by body weight and response to exercise training varies according to anatomical location

Ronja Ojala MD,  Jaakko Hentilä PhD,  Martin S. Lietzén MD,  Milja Arponen MSc,  Marja A. Heiskanen PhD,  Sanna M. Honkala PhD,  Heidi Virtanen MB,  Kalle Koskensalo MSc,  Riikka Lautamäki MD,  Eliisa Löyttyniemi PhD,  Riitta Parkkola MD,  Olli J. Heinonen MD,  Tarja Malm PhD,  Leo Lahti PhD,  Juha Rinne MD,  Olli Eskola PhD,  Johan Rajander MSc,  Kirsi H. Pietiläinen MD,  Jaakko Kaprio MD,  Kaisa K. Ivaska PhD,  Jarna C. Hannukainen PhD, 
  • Pages: 251-261
  • First Published: 11 October 2023

Effect of tirzepatide on glycaemic control and weight loss compared with other glucagon-like peptide-1 receptor agonists in Japanese patients with type 2 diabetes mellitus

Shunichiro Tsukamoto MD,  Shohei Tanaka MD,  Takayuki Yamada PhD,  Kazushi Uneda PhD,  Kengo Azushima PhD,  Sho Kinguchi PhD,  Hiromichi Wakui PhD,  Kouichi Tamura PhD, 
  • Pages: 262-274
  • First Published: 12 October 2023

Incremental burden on health-related quality of life, health service utilization and direct medical expenditures associated with cognitive impairment among non-institutionalized people with diabetes aged 65 years and older

Dawei Guan MD,  Motomori O. Lewis BS,  Piaopiao Li MS,  Yichen Zhang PhD,  Ping Zhang PhD,  Shichao Tang PhD,  Joshua Brown PharmD,  Jingchuan Guo MD,  Yongkang Zhang PhD,  Hui Shao MD, 
  • Pages: 275-282
  • First Published: 03 October 2023
Open Access

The relationship between glycated haemoglobin and blood glucose-lowering treatment trajectories in type 2 diabetes: The Fremantle Diabetes Study Phase II

Timothy M. E. Davis FRACP,  Wendy Davis PhD, 
  • Pages: 283-292
  • First Published: 05 October 2023

Time trends towards earlier puberty in boys and girls with type 1 diabetes: Insights from the German Diabetes Prospective Follow-up (DPV) registry, 2000 to 2021

Bettina Gohlke MD,  Felix Reschke MD,  Stefanie Lanzinger PhD,  Claudia Boettcher MD,  Gitta Gemulla MD,  Susanne Thiele-Schmitz MD,  Désirée Dunstheimer MD,  Louise van den Boom MD,  Joachim Woelfle MD,  Reinhard W. Holl MD, 
  • Pages: 293-300
  • First Published: 12 October 2023
Open Access

Associations of bolus insulin injection frequency and smart pen engagement with glycaemic control in people living with type 1 diabetes

Jarl Hellman MD,  Niels Væver Hartvig PhD,  Anne Kaas MD,  Jonas Bech Møller PhD,  Mads Reinholdt Sørensen PhD,  Johan Jendle MD, 
  • Pages: 301-310
  • First Published: 05 November 2023
Open Access

Ultra-rapid lispro improved postprandial glucose control compared to insulin lispro in predominantly Chinese patients with type 1 diabetes: A prospective, randomized, double-blind phase 3 study

Jianhua Ma MD,  Xiang Yan MD,  Qiong Feng MD,  Wei Liu MD,  Federico Pérez Manghi MD,  Pedro García-Hernández MD,  Guixia Wang MD,  Jianwei Xu MD,  Yuan Yuan PhD,  Zhiguang Zhou MD, 
  • Pages: 311-318
  • First Published: 23 October 2023
Open Access

Tirzepatide reduces the predicted risk of atherosclerotic cardiovascular disease and improves cardiometabolic risk factors in adults with obesity or overweight: SURMOUNT-1 post hoc analysis

Emily R. Hankosky PhD,  Hui Wang PhD,  Lisa M. Neff MD,  Hong Kan PhD,  Fangyu Wang MS,  Nadia N. Ahmad MD,  Ryan Griffin PhD,  Adam Stefanski MD,  W. Timothy Garvey MD, 
  • Pages: 319-328
  • First Published: 06 November 2023
Open Access

Sustained metabolic benefits of ΔTRTX-Ac1, a tarantula venom-derived peptide, when administered together with exenatide in high-fat fed mice

Aimee Coulter-Parkhill PhD,  Neil Tanday PhD,  Diego Cobice PhD,  Christopher M. McLaughlin PhD,  Stephen McClean PhD,  Victor A. Gault PhD,  Nigel Irwin PhD, 
  • Pages: 329-338
  • First Published: 11 October 2023
Open Access

Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model

Kálmán Bódis MD,  Saida Breuer PhD,  Assja Crepzia-Pevzner MSc,  Oana-Patricia Zaharia MD,  Martin Schön PhD,  Nina Saatmann MSc,  Delsi Altenhofen PhD,  Christian Springer PhD,  Julia Szendroedi MD,  Robert Wagner MD,  Hadi Al-Hasani PhD,  Michael Roden MD,  Dominik Pesta PhD,  Alexandra Chadt PhD,  for the GDS Group , 
  • Pages: 339-350
  • First Published: 23 October 2023
Open Access

Distinct effects of type 2 diabetes and obesity on cardiopulmonary performance

Lorenzo Nesti MD,  Nicola Riccardo Pugliese MD,  Lorenza Santoni MD,  Silvia Armenia PhD,  Martina Chiriacò MD,  Luca Sacchetta MD,  Nicolò De Biase MD,  Lavinia Del Punta MD,  Stefano Masi MD,  Domenico Tricò MD,  Andrea Natali MD, 
  • Pages: 351-361
  • First Published: 12 October 2023

Effects of continuous glucose monitoring on glycaemic control in type 2 diabetes: A systematic review and network meta-analysis of randomized controlled trials

Jiaping Lu MD,  Zhen Ying PhD,  Ping Wang MD,  Minjie Fu PhD,  Chenyu Han MD,  Min Zhang PhD, 
  • Pages: 362-372
  • First Published: 12 October 2023

Sex-specific causality of MRI-derived body compositions on glycaemic traits: Mendelian randomization and observational study

Yijie Zhu MD,  Qi Wang MD,  Huajie Dai MD,  Tianzhichao Hou MD,  Tiange Wang PhD,  Zhiyun Zhao PhD,  Mian Li PhD,  Wei Miao BD,  Jian Yang BD,  Jieli Lu PhD,  Yu Xu PhD,  Yuhong Chen PhD,  Guang Ning PhD,  Jie Zheng PhD,  Yufang Bi PhD,  Min Xu PhD,  Weiqing Wang PhD, 
  • Pages: 373-384
  • First Published: 03 November 2023

RESEARCH LETTERS

Open Access

The effect of empagliflozin and fenofibrate therapies, alone and in combination, on the serum urate concentration in hyperuricaemic type 2 diabetes

Timothy M. E. Davis FRACP,  Sharon Maxwell BSc(Nurs),  Cathy Chan MPH,  Helen I. Keen FRACP,  Wendy A. Davis PhD, 
  • Pages: 385-388
  • First Published: 19 September 2023
Open Access

The glycaemic roller coaster phenomenon in type 1 diabetes

Mia Christensen MD,  Esben Lerkevang Grove Laugesen MD,  Bo M. Bibby MSc,  Klavs W. Hansen MD, 
  • Pages: 389-391
  • First Published: 28 September 2023

Is composite cardiovascular death or hospitalization for heart failure a valid surrogate for mortality in patients treated with sodium-glucose cotransporter 2 inhibitors? A correlation meta-analysis

Alhassane Diallo MD,  Miguel Carlos-Bolumbu MD,  Florence Galtier MD, 
  • Pages: 392-395
  • First Published: 18 October 2023
Open Access

Impact on glycated haemoglobin and body weight changes after stopping tirzepatide for 4 weeks in the SURPASS-1 monotherapy trial

Julio Rosenstock MD,  Clare J. Lee MD,  Laura Fernández Landó MD,  Minzhi Liu PhD,  Chrisanthi A. Karanikas MS,  Vivian T. Thieu PhD, 
  • Pages: 396-399
  • First Published: 25 October 2023

LETTERS TO THE EDITOR

Breaking a feedback loop: A reassessment of an investigator initiated OS-AID study

Katarina Braune MD,  Sufyan Hussain MD,  Rayhan Lal MD,  Scott Leibrand BS,  Dana M. Lewis BA,  Shane O'Donnell PhD, 
  • Pages: 400-402
  • First Published: 05 October 2023

Letter of reply to ‘Breaking a feedback loop: A reassessment of an investigator-initiated OS-AID study’ by Braune et al.

Juri Künzler MD,  Markus Laimer MD,  Andreas Melmer MD, 
  • Pages: 403-404
  • First Published: 20 October 2023